Pharmacokinetics

More sensitive CAR-T positive cell detection

Flow Cytometry qPCR

Why do we detect CAR-T positive cells?

For CAR-T cells, the effective ingredient for tumor killing is CAR positive T cells. In addition, the number of CAR-T positive cells of patients is closely related to clinical effectiveness and clinical side effects.

What is the mechanism for detecting CAR-T positive cells?

At present, the most commonly used technique in clinical is flow cytometry, which is based on the specific combination of antigen and antibody, and excites a fluorescent group to produce a fluorescent signal, thus allows the identification of positive cells.

BioSwan's product
advantages

sensitivity

High sensitivity up to 1:100,000

specificity

Better specificity and no recognition of other CAR signals

accuracy

Good accuracy and high affinity to clearly define positive and negative CAR-T cell subpopulations

STABILITY

Good stabillity with minimal batch-to- batch varlation

Product List

USE	Catalog	product	Specification
Anti-CD19 CAR-T Cell Detection Reagent	200102	Rabbit Anti-Mouse FMC63 scFv Monoclonal Antibody, Alexa Fluor 647	100 tests
	200106	Rabbit Anti-Mouse FMC63 scFv Monoclonal Antibody, PE	100 tests
	300406	Mouse Anti-Mouse FMC63 scFv Monoclonal Antibody, PE	100 tests
	300402	Mouse Anti-Mouse FMC63 scFv Monoclonal Antibody, Alexa Fluor 647	100 tests
CMA CAR-T Cell Detection Reagent	200702	Rabbit Anti-Mouse C11D5.3 scFv Monoclonal Antibody, Alexa Fluor 647	100 tests
	200706	200706 Rabbit Anti-Mouse C11D5.3 scFv Monoclonal Antibody, PE	100 tests
	401502	Human BCMA / TNFRSF17 Protein, Fc Tag, Alexa Fluor 647	100 tests

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Pharmacokinetics

More sensitive CAR-T positive cell detection

The first companion diagnostic product in China

Product List